mLin28 载体

基因信息

基因名称mLin28
类型ORF
子类Pluripotency gene
描述Mouse lin-28 homolog A gene. Encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in development, self-renewal of embryonic stem cells and metabolism. Highly expressed in mouse embryonic stem cells and during early embryogenesis.
应用注释It is dispensable for maintaining pluripotency. Can be used to promote efficient reprogramming of a variety of cell types. Regulate the self-renewal of stem cells. Overexpression in mice can cause gigantism and a delay in puberty onset. Enhances tissue repair in some adult tissues by reprogramming cellular bioenergetics. Can promote the expression of some metabolic enzymes. Can regulate glucose homeostasis in mammals and promote resistance to high fat diet-induced obesity and type 2 diabetes.
参考文献Cell. 155: 778 (2013); Cell Stem Cell. 19:66 (2016)
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载体描述	载体类型	标记基因	价格
mLin28 expression regular plasmid 载体	Mammalian Gene Expression Vector 指南		￥1180 起
mLin28 expression lentivirus 载体	Mammalian Gene Expression Lentiviral Vector 指南		￥1180 起
mLin28 expression adenovirus 载体	Mammalian Gene Expression Adenoviral Vector 指南		￥1180 起
mLin28 expression AAV病毒载体载体	Mammalian Gene Expression AAV Vector 指南	--	￥1180 起
mLin28 expression PiggyBac转座载体载体	Mammalian Gene Expression PiggyBac Vector 指南		￥1180 起

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