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小而强大:AAV如何成为基因治疗研发的核心病毒载体
小而强大:AAV如何成为基因治疗研发的核心病毒载体
Adeno-associated virus (AAV) is a popular viral vector used for gene delivery and has rapidly overtaken other delivery systems as the vector of choice for in vivo applications and therapeutics development. This is largely due to its enhanced safety p...
成功的CRISPR文库筛选需要做哪些准备?
成功的CRISPR文库筛选需要做哪些准备?
CRISPR screening is a widely used technique in biological research, offering a powerful approach for identifying genes associated with a biological process and investigating gene function. By introducing whole-genome or pathway-specific gRNA librarie...
什么是血清型?带您了解AAV血清型和相关变体
什么是血清型?带您了解AAV血清型和相关变体
AAV is emerging as a popular tool for gene delivery in the lab and in the clinic but deciding which serotype to use when first starting your experiment can seem like an overwhelming task. Although a broad base of literature exists to help guide your...
mRNA疗法简介
mRNA疗法简介
mRNA therapeutics are emerging in popularity, thanks in part to their widespread use in COVID-19 vaccination, but what exactly makes mRNA a good therapeutic? To answer that question let’s first dive into the basics of an mRNA molecule. mRNA structure...
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